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LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN-1
Descriptors Found:
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DeCS
Descriptor
English
:
Lymphocyte Function-Associated Antigen-1
Descriptor
Spanish
:
Antígeno-1 Asociado a Función de Linfocito
Descriptor
Portuguese
:
Antígeno-1 Associado à Função Linfocitária
Synonyms
English
:
Integrin alphaLbeta2
Antigen-1, Lymphocyte Function-Associated
alphaLbeta2, Integrin
Leukocyte Function Associated Antigen-1
LFA-1
Tree Number:
D12.776.395.550.200.625.550
D12.776.543.550.200.625.550
D12.776.543.750.705.408.600.400
D12.776.543.750.705.877.550
D23.050.301.264.035.111.400
D23.050.301.264.035.850.550
D23.050.301.350.625.550
D23.101.100.110.111.400
D23.101.100.110.850.550
Definition
English
:
An integrin heterodimer widely expressed on cells of hematopoietic origin. CD11A
ANTIGEN
comprises the alpha chain and the CD18
antigen
(
ANTIGENS
, CD18) the beta chain.
Lymphocyte function-associated antigen-1
is a major receptor of T-CELLS; B-CELLS; and
GRANULOCYTES
. It mediates the leukocyte adhesion reactions underlying cytolytic conjugate formation, helper T-cell interactions, and antibody-dependent killing by NATURAL KILLER CELLS and
granulocytes
. Intracellular adhesion molecule-1 has been defined as a ligand for
lymphocyte function-associated antigen-1.
Indexing Annotation
English
:
DF: LFA1 or LFA 1
History Note
English
:
91
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CH
chemistry
CL
classification
CT
contraindications
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
29009
Unique Identifier:
D016169
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
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